How much is Entresto with Medicare in Arizona in 2026?

These are national Medicare figures from CMS, not Arizona-only prices. Entresto is used to treat certain types of heart failure. What you pay at a pharmacy in Chandler or anywhere in Arizona depends on your plan's deductible, the tier Entresto sits on, and whether you have reached the yearly cap.

Entresto under Medicare Part D: price and cost figures

Measure	Figure
Medicare negotiated price, 30-day supply (2026)	$295
List price CMS reported before negotiation, 30-day supply	$628
Average gross Part D cost per claim, 2025 (national)	$1,077.74
Average gross Part D cost per claim, Q1 2026 (national, preliminary)	$325.48
People with Part D who used it in 2025 (national)	826,563
Part D out-of-pocket cap, 2026 / 2027	$2,100 / $2,400

How Part D pricing works for this drug

Your plan pays the pharmacy a negotiated price, and your share comes in three steps, in this order:

Step 1, the deductible: you pay the full negotiated price until your plan's deductible is met. The highest Part D deductible in the CMS landscape for Maricopa County is $615 for 2026 and $700 for 2027. Some plans have a lower deductible or none on certain tiers.

Step 2, your tier: after the deductible you pay the copay (a flat dollar amount) or coinsurance (a percentage of the price) set by the tier Entresto sits on in your plan.

Step 3, the yearly cap: once your out-of-pocket drug spending reaches $2,100 in 2026 ($2,400 in 2027), you pay $0 for covered Part D drugs for the rest of the year.

In 2025, 826,563 people with Part D filled Entresto, at an average gross cost of $1,077.74 per claim. A claim can be a 30-day or 90-day fill, so treat that as a guide to scale, not a monthly bill.

What changes the answer

Entresto is changing fast. CMS lists it as removed from the negotiation program effective January 1, 2027, which happens once a generic is marketed, and brand-name claims have dropped: 826,563 people with Part D used Entresto in 2025, against 103,676 in the first quarter of 2026. Ask whether generic sacubitril/valsartan is on your 2027 plan and on which tier.

Formularies are set plan by plan. The 2027 drug lists are published by each plan for Annual Enrollment, and CMS has not yet released its 2027 formulary files, so check your own plan's 2027 list and tier. People with limited income can apply for Extra Help through Social Security, which lowers drug copays.

What to do next

Bring your prescription list to a plan review. During Annual Enrollment, October 15 to December 7, 2026, we compare how Entresto is covered on the 2027 plans we offer in Maricopa and Pinal counties, including tier, deductible and pharmacy, and show you the yearly total rather than one copay.

Related questions

Sources

1. CMS Medicare Quarterly Part D Spending by Drug Centers for Medicare & Medicaid Services
2. CMS fact sheet: negotiated prices for initial price applicability year 2026 Centers for Medicare & Medicaid Services
3. CMS: Selected drugs and negotiated prices Centers for Medicare & Medicaid Services
4. CMS Medicare Advantage and Part D Landscape, Contract Year 2027 Centers for Medicare & Medicaid Services

Please note: We do not offer every plan available in your area. Currently we represent 34 organizations which offer 64 products in your area. Please contact Medicare.gov, 1-800-MEDICARE, or your local State Health Insurance Program (SHIP) to get information on all of your options.Rise Up Benefits Group is not connected with or endorsed by the United States government or the federal Medicare program. Medicare has neither endorsed nor reviewed this information.